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Taysha Gene Therapies Faces Setback in Development of TSHA120 Program

Elaine Mendonça by Elaine Mendonça
September 19, 2023
in News
Reading Time: 4 mins read
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Taysha Gene Therapies, a leading biotech company, has recently made a significant decision regarding its TSHA-120 program in Giant Axonal Neuropathy (GAN). Unfortunately, due to feedback received from the U.S. FDA, Taysha has decided to discontinue the development of this program. This decision was primarily driven by challenges encountered in the feasibility of the study design, which is crucial for the potential Biologics License Application (BLA) submission.

In addition to this, Taysha also revealed that Astellas Gene Therapies, Inc. has chosen not to exercise its option to obtain an exclusive license to TSHA-120 under the Option Agreement. This unexpected turn of events has brought about a shift in the company’s plans for the program.

During the company’s R&D Day, Taysha had previously shared clinical updates on the investigational program TSHA-120 in GAN. They had expressed confidence in the results of comprehensive data analysis and the development of a disease progression model (DPM), which they believed had successfully addressed the FDA’s recommendations. However, the recent feedback from the FDA has forced Taysha to make the difficult decision of discontinuing the program altogether.

This news undoubtedly comes as a disappointment to both Taysha Gene Therapies and the medical community, as the potential of TSHA-120 in treating Giant Axonal Neuropathy was highly anticipated. However, the company remains committed to its mission of advancing gene therapies and will undoubtedly redirect its focus towards other promising avenues in the field.

As of September 19, 2023, Taysha Gene Therapies has taken a step back from the development of TSHA-120, but this setback will undoubtedly fuel their determination to continue making groundbreaking strides in the gene therapy landscape.

Taysha Gene Therapies, Inc.

TSHA

Buy

Updated on: 19/09/2023

Financial Health

Healthy


Debt to equity ratio: Strong Buy

Price to earnings ratio: Neutral

Price to book ratio: Strong Buy

DCF: Strong Buy

ROE: Strong Sell

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Price Target

Current $3.26

Concensus $28.17


Low $1.50

Median $39.00

High $44.00

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Social Sentiments

4:00 AM (UTC)

Date:19 September, 2023

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Analyst Ratings

Analyst / firm Rating
Jefferies Sell
Matthew Harrison
Morgan Stanley
Buy
Kristen Kluska
Cantor Fitzgerald
Buy
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TSHA Stock Performance Fluctuates on September 19, 2023: Positive Earnings Growth but Limited Data for Assessment

TSHA stock, belonging to the biotechnology industry within the health technology sector, experienced fluctuations in its performance on September 19, 2023. The stock had a previous close of $3.10 and opened at the same price. Throughout the day, its range fluctuated between $3.06 and $3.28. The trading volume for the day was 87,884, which is significantly lower than the average volume of 3,471,828 over the past three months. The market capitalization of TSHA stands at $613.2 million.

In terms of earnings growth, TSHA has shown positive trends. Last year, the company experienced a growth rate of 18.51%, and this year, it has seen a substantial increase of 70.58%. Looking towards the future, the projected earnings growth for the next five years is estimated to be around 2.00%.

Unfortunately, there is no available data on TSHA’s competitors, making it difficult to analyze its competitive position within the industry.

Looking ahead, TSHA’s next reporting date is scheduled for November 8, 2023. Analysts forecast an earnings per share (EPS) of -$0.28 for the current quarter. In the previous year, TSHA reported an annual revenue of $2.5 million, but the company suffered a net loss of -$166.0 million. This resulted in a net profit margin of -6,635.25%, indicating significant losses.

In summary, TSHA stock experienced fluctuations in its performance on September 19, 2023. While the company has shown positive earnings growth, its lack of available revenue data and missing P/E ratio make it challenging to fully assess its financial performance. Investors should closely monitor TSHA’s upcoming reporting date for further insights into the company’s financial health.

Taysha Gene Therapies Inc: Positive Outlook for Potential Growth in Gene Therapy Industry

Taysha Gene Therapies Inc (TSHA) is a company that has been attracting attention from investors due to its potential for growth in the gene therapy industry. On September 19, 2023, the stock’s performance was closely analyzed, and the findings were quite positive.

According to data from CNN Money, there are nine analysts offering 12-month price forecasts for TSHA stock. The median target price is $6.00, with a high estimate of $8.00 and a low estimate of $2.00. This indicates that the analysts have a generally optimistic outlook for the stock’s future performance.

Furthermore, the median estimate represents an 85.19% increase from the last recorded price of $3.24. This suggests that there is significant potential for growth in the coming months, according to the consensus of these analysts.

The consensus among the nine polled investment analysts is to buy stock in Taysha Gene Therapies Inc. This rating has remained steady since July, indicating a consistent positive sentiment towards the company’s prospects. This continued buy rating suggests that investors believe in the company’s ability to deliver strong results and generate value for shareholders.

While the stock’s current quarter earnings per share stand at -$0.28, indicating a loss, it is important to note that gene therapy companies often operate at a loss in the early stages of their development. The focus is typically on research and development, which incurs significant costs. However, with sales of $2.4 million reported for the current quarter, Taysha Gene Therapies Inc is showing promising revenue generation potential.

Investors should keep an eye on the reporting date of November 8, as it will provide further insights into the company’s financial performance and any updates on its gene therapy pipeline. This information could potentially impact the stock’s future performance.

In conclusion, Taysha Gene Therapies Inc’s stock performance on September 19, 2023, suggests positive sentiment among analysts and investors. With a consensus buy rating and a median target price indicating a significant increase, the stock is poised for potential growth. However, investors should remain cautious and monitor the company’s financial updates and any developments in the gene therapy industry.

Tags: TSHA
Elaine Mendonça

Elaine Mendonça

Over the last nine years, Elaine has managed investment portfolio using fundamental analysis and value investing, emphasizing long-term time horizons.

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