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Last update: Nov 3, 2026, 10:20 AM ET
Madrigal Pharmaceuticals, Inc.
$431.16▲ 0.19% at Nov 2 close
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Why Madrigal Pharmaceuticals, Inc. (MDGL) stock moved

Updated Nov 2, 2026

Madrigal Pharmaceuticals, Inc. (MDGL) shares rose 0.2% to $431.16 at the November 2, 2026 close, a slight gain from the prior close of $430.36. That close is the latest confirmed price for MDGL; a live quote was not available. BestStocks flagged the session as a major change for MDGL. The move is tied to an earnings beat. Below, we break down what changed for MDGL, why it matters for investors, how the stock reacted, and the catalysts on the calendar.

What happened

Earnings Beat

Madrigal Pharmaceuticals, Inc. (MDGL) reported EPS of $1.83 vs. consensus estimate of -$0.86, beating by 312.1% on November 3, 2026. MDGL earnings scheduled for February 18, 2027, with current consensus EPS estimate of -$0.11.

This summary describes the catalyst and move as first detected on Nov 3, 2026, 10:08 AM EST; the stock has continued trading since, so the current price and percentage move (shown above) may be larger or smaller than the figures here.
Material / EarningsLow confidence
Rel. volume
—
Calculating
Vs peers
—
No comparable peers
Market cap
—
Earnings in
0d
2026-11-03
Price chart
Oct 5 – Nov 3
EVFVNNVNN$429$463$497Oct 5Oct 12Oct 20Oct 27Nov 3
E earnings
F filing
A analyst
V/N other
click a marker to highlight
Change events — click to jump to details

What it means for Madrigal Pharmaceuticals, Inc. investors

For Madrigal Pharmaceuticals, Inc. investors, the recent signals are mixed, leaving the near-term picture neutral / mixed. On the constructive side: Earnings beat with positive market reaction; Positive 0.2% session move. Weighing against that: Madrigal Pharmaceuticals (MDGL) declined 2.60% to $455.03, driven primarily by technical weakness and valuation reassessment rather than operational news; Madrigal Pharmaceuticals filed an 8-K material event report today (SEC mdgl-20260730.htm) coinciding with an earnings report, triggering a 14.28% intraday decline to $468.76. BestStocks rates the overall signal quality low (41/100). With earnings due imminently, the next report is the most likely near-term test of the move.

MDGL price reaction

MDGL last traded at $431.16, up $0.80 (+0.19%) from the previous close of $430.36. Over the past month the stock has ranged between $430.36 and $496.45, and it currently sits about 1% of the way up that band.

The bull and bear case for MDGL stock

Latest catalyststrengthens the bull case
The latest catalyst — an earnings beat the market rewarded — it strengthens the bull case.

Weighing the constructive signals against the risks, here is how the bull and bear case for Madrigal Pharmaceuticals, Inc. (MDGL) lines up on the latest data.

The bullish case

  • Earnings beat with positive market reaction.
  • Positive 0.2% session move.
  • Madrigal Pharmaceuticals rallied 10.48% to $476.35 following confirmation of today's earnings report filing.

The bearish case

  • Madrigal Pharmaceuticals (MDGL) declined 2.60% to $455.03, driven primarily by technical weakness and valuation reassessment rather than operational news.
  • MDGL fell 2.54% in early trading despite announcing that its collaboration with Ribo reached a first major milestone in advancing novel siRNA therapies for MASH (metabolic dysfunction-associated steatohepatitis).
Bull vs bear balanceNeutral / Mixed
BearishNeutralBullish
The latest catalyst moved the balance toward the bulls — the hollow tick marks where it sat before.

Weighing both sides, BestStocks' composite read of recent signals is roughly balanced, as the bull-versus-bear meter above shows. This is an educational summary of the bull and bear case, not investment advice.

Analyst expectations
No analyst data available
SEC filings watch
8-K2026-11-03
Material event — review for impact
high
10-Q2026-11-03
Quarterly financial results
medium
8-K2026-08-12
Material event — review for impact
high
8-K2026-07-30
Material event — review for impact
high
Peer context
MDGL+0.2%

Previous notable changes for MDGL

Activity2026-11-03+0.0%
Madrigal Pharmaceuticals rallied 10.48% to $476.35 following confirmation of today's earnings report filing. The move reflects investor reaction to reported results, though specific financial metrics and guidance details are not yet available in the evidence.
Filings2026-11-03+0.0%
Madrigal Pharmaceuticals, Inc. (MDGL) filed a new 10-Q on November 3, 2026.
News2026-10-27+0.6%
Madrigal lacks key factors typically needed to beat upcoming earnings expectations.
Valuation2026-10-23-4.2%via Yahoo Finance ↗
Madrigal Pharmaceuticals fell 2.30% to $442.92, driven by Bank of America Securities lowering its price target to $533 from $543 and maintaining a Neutral rating, citing a lack of near-term clinical catalysts in the sector (web_catalyst). The decline also reflects pre-earnings positioning ahead of Q3 2026 results scheduled for November 3. Volume of 57,298 shares traded in the first 180 minutes is running at 0.42x the historical average for this time of day.

In-depth MDGL event analyses

Permanent, dated analyses of MDGL's most significant sessions.
Upcoming catalysts & outlook
Next earnings
2026-11-03
in 0 days
Thesis shift
Neutral / Mixed
bullish signal
Risk level
High
from change events

Frequently asked questions about MDGL

Why did Madrigal Pharmaceuticals, Inc. (MDGL) stock move?

MDGL rose 0.2% to $431.16. The move is associated with an earnings beat.

How much did MDGL stock rise?

MDGL gained 0.19% ($0.80) versus the prior close of $430.36, last trading at $431.16.

When is Madrigal Pharmaceuticals, Inc.'s next earnings date?

MDGL's next earnings report is scheduled for 2026-11-03 — about 0 days away.

How BestStocks tracks MDGL

This page is generated automatically by BestStocks' change-detection system after an earnings beat was detected and verified against independent data sources. It draws on 20 tracked change events for MDGL, cross-checked against the data sources listed below. A live intraday quote was not available, so price and volume figures are the confirmed end-of-day close from November 2, 2026 — not the current price — and the percentage move is that session's. They refresh once live quotes resume. For companies with multiple share classes, market-cap figures can differ by data source. Analyst price targets and ratings are FMP consensus. This is an educational summary of what changed and why — not personalized investment advice.

Data sources
FMP real-time & historical price dataFMP earnings & estimatesSEC EDGAR filingsCompany news feedsEarnings calendar (FMP)
Educational research tool — not personalized investment advice. Data may be delayed.