Market closed · After hours · 4:55 PM ET
Last update: Nov 3, 2026, 4:52 PM ET
Mirum Pharmaceuticals, Inc.
$87.03▲ 1.50% today
After Hours

Why Mirum Pharmaceuticals, Inc. (MIRM) stock moved

Updated Nov 3, 2026

Mirum Pharmaceuticals, Inc. (MIRM) shares rose 1.5% to $87.03 as of November 3, 2026, a modest gain from the prior close of $85.74. BestStocks flagged the session as a major change for MIRM. The move is tied to an earnings miss. Below, we break down what changed for MIRM, why it matters for investors, how the stock reacted, and the catalysts on the calendar.

What happened

Earnings Miss

Mirum Pharmaceuticals, Inc. (MIRM) reported EPS of −$0.87 vs. consensus estimate of −$0.49, missing by 78.7% on 2026-11-03. MIRM's next earnings are scheduled for 2027-02-24, with consensus EPS estimate of −$0.58.

This summary describes the catalyst and move as first detected on Nov 3, 2026, 4:38 PM EST; the stock has continued trading since, so the current price and percentage move (shown above) may be larger or smaller than the figures here.
Material / EarningsLow confidence
Rel. volume
0.9×
Below Avg
Vs peers
—
No comparable peers
Market cap
$5.7B
NASDAQ Global Market
Analyst target
$153
+76.0% vs price
Price chart
Oct 5 – Nov 3
ENNNVNVNFNNF$79$83$87Oct 5Oct 12Oct 20Oct 27Nov 3
E earnings
F filing
A analyst
V/N other
click a marker to highlight
Change events — click to jump to details

What it means for Mirum Pharmaceuticals, Inc. investors

For Mirum Pharmaceuticals, Inc. investors, the recent signals add up to a bearish shift. On the constructive side: Positive 1.5% session move; Mirum Pharmaceuticals, Inc. (MIRM) moved +5.49% from $95.41 to $100.65 on 2026-08-07. Weighing against that: Earnings missed expectations; Mirum Pharmaceuticals shares fell 5.85% to $93.04 as investors weigh regulatory uncertainties ahead of a September 26 FDA decision on zilurgisertib for FOP and recent FDA requests for additional Phase 3 clarity on volixibat, according to the web_catalyst synthesis. Wall Street's consensus price target sits at $153.20, implying +76.0% upside from $87.03. BestStocks rates the overall signal quality low (55/100). With earnings roughly 113 days out, the next report is the most likely near-term test of the move.

MIRM price reaction

MIRM last traded at $87.03, up $1.29 (+1.50%) from the previous close of $85.74. The session traded on 0.9× average volume (below avg), so participation was unremarkable. Over the past month the stock has ranged between $79.25 and $87.03, and it currently sits about 100% of the way up that band.

Bullish and bearish analyst opinions on Mirum Pharmaceuticals, Inc. (MIRM)

Latest catalysta bearish counterpoint
The latest catalyst — an earnings miss — a bearish counterpoint that challenges the prevailing bullish analyst view.

The consensus analyst price target on Mirum Pharmaceuticals, Inc. (MIRM) is $153.20, 76.0% above the recent $87.03. Over the past 90 days analysts logged 0 upgrades, 15 maintains, and 0 downgrades. Here is how the bullish and bearish cases on MIRM line up.

The bullish case

  • Wall Street's consensus price target of $153.20 implies +76.0% upside from $87.03.
  • The Street's most bullish target is $200.00 (+129.8%).
  • Positive 1.5% session move.
  • Mirum Pharmaceuticals, Inc. (MIRM) moved +5.49% from $95.41 to $100.65 on 2026-08-07.

The bearish case

  • Earnings missed expectations.
  • Mirum Pharmaceuticals shares fell 5.85% to $93.04 as investors weigh regulatory uncertainties ahead of a September 26 FDA decision on zilurgisertib for FOP and recent FDA requests for additional Phase 3 clarity on volixibat, according to the web_catalyst synthesis.
Bull vs bear balanceBearish Shift
BearishNeutralBullish
The latest catalyst moved the balance toward the bears — the hollow tick marks where it sat before.

Weighing both sides, BestStocks' composite read of recent signals is bearish, as the bull-versus-bear meter above shows. This is an educational summary of the bull and bear case, not investment advice.

Analyst price targets and ratings are FMP consensus figures as of Nov 3, 2026; other aggregators may differ. High and low targets show the range of estimates, not forecasts.

Analyst expectations
Consensus target: $153+76.0%
= 15 maintains
TD Cowen maintained Buy · 2026-10-21
SEC filings watch
8-K2026-10-26
Material event — review for impact
high
8-K2026-10-13
Material event — review for impact
high
8-K2026-09-28
Material event — review for impact
high
8-K2026-09-08
Material event — review for impact
high
Peer context
MIRM+1.5%

Previous notable changes for MIRM

News2026-11-02+0.9%
Mirum presented new clinical data across its rare liver disease portfolio at AASLD's 2026 meeting.
News2026-10-27+2.8%
Mirum Pharmaceuticals expected to beat earnings estimates in upcoming Q3 report.
News2026-10-26+3.6%
Mirum reports positive Phase 2b results for zilurgisertib in pediatric patients aged 6 and older.
Filings2026-10-26+3.6%
Mirum Pharmaceuticals, Inc. (MIRM) filed an 8-K on October 26, 2026. The filing content was not detailed in available sources.

In-depth MIRM event analyses

Permanent, dated analyses of MIRM's most significant sessions.
Upcoming catalysts & outlook
Next earnings
2027-02-24 (est.)
in 113 days
Earnings Release
2027-02-24
High impact
Thesis shift
Bearish Shift
bearish signal
Risk level
Medium
from change events

Frequently asked questions about MIRM

Why did Mirum Pharmaceuticals, Inc. (MIRM) stock move?

MIRM rose 1.5% to $87.03. The move is associated with an earnings miss.

How much did MIRM stock rise?

MIRM gained 1.50% ($1.29) versus the prior close of $85.74, last trading at $87.03 on 0.9× average volume.

When is Mirum Pharmaceuticals, Inc.'s next earnings date?

MIRM's next earnings report is estimated for 2027-02-24 — about 113 days away.

What is the analyst price target for MIRM?

The consensus analyst price target for MIRM is $153.20, about 76.0% above the current $87.03. Over the past 90 days, analysts recorded 0 upgrades, 15 maintains, and 0 downgrades.

How BestStocks tracks MIRM

This page is generated automatically by BestStocks' change-detection system after an earnings miss was detected and verified against independent data sources. It draws on 20 tracked change events for MIRM, cross-checked against the data sources listed below. Price, volume, and market-capitalization figures are the live intraday quote as of November 3, 2026 and refresh as new information is detected; for companies with multiple share classes, market-cap figures can differ by data source. Analyst price targets and ratings are FMP consensus. This is an educational summary of what changed and why — not personalized investment advice.

Data sources
FMP real-time & historical price dataFMP earnings & estimatesSEC EDGAR filingsAnalyst ratings & price targets (FMP)Earnings calendar (FMP)
Educational research tool — not personalized investment advice. Data may be delayed.