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Last update: Oct 13, 2026, 6:14 PM ET
Arrowhead Pharmaceuticals, Inc.
$58.13▼ 4.28% today
Pre-market

Why Arrowhead Pharmaceuticals, Inc. (ARWR) stock moved

Updated Oct 14, 2026

Arrowhead Pharmaceuticals, Inc. (ARWR) shares fell 4.3% to $58.13 as of October 14, 2026, a moderate decline from the prior close of $60.73. BestStocks flagged the session as a major change for ARWR. Below, we break down what changed for ARWR, why it matters for investors, how the stock reacted, and the catalysts on the calendar.

What happened

ARWR fell 4.3% to $58.13

ARWR fell 4.3% in its latest session, moving from $60.73 to $58.13.

ValuationLow confidence
Rel. volume
1.1×
Normal
Vs peers
—
No comparable peers
Market cap
$8.2B
NASDAQ Global Select
Analyst target
$101
+73.1% vs price
Price chart
Sep 14 – Oct 14
VVNNVVVVVENN$58$69$81Sep 14Sep 22Sep 29Oct 7Oct 14
E earnings
F filing
A analyst
V/N other
click a marker to highlight
Change events — click to jump to details

What it means for Arrowhead Pharmaceuticals, Inc. investors

For Arrowhead Pharmaceuticals, Inc. investors, the recent signals add up to a strong bearish shift. Weighing against that: Material negative event; Negative session, down 4.3%. Wall Street's consensus price target sits at $100.63, implying +73.1% upside from $58.13. BestStocks rates the overall signal quality low (55/100). With earnings roughly 41 days out, the next report is the most likely near-term test of the move.

ARWR price reaction

ARWR last traded at $58.13, down $2.60 (-4.28%) from the previous close of $60.73. The session traded on 1.1× average volume (normal), so participation was unremarkable. Over the past month the stock has ranged between $58.13 and $80.67, and it currently sits about 0% of the way up that band.

Bullish and bearish analyst opinions on Arrowhead Pharmaceuticals, Inc. (ARWR)

The consensus analyst price target on Arrowhead Pharmaceuticals, Inc. (ARWR) is $100.63, 73.1% above the recent $58.13. Over the past 90 days analysts logged 0 upgrades, 10 maintains, and 0 downgrades. Here is how the bullish and bearish cases on ARWR line up.

The bullish case

  • Wall Street's consensus price target of $100.63 implies +73.1% upside from $58.13.
  • The Street's most bullish target is $126.00 (+116.8%).

The bearish case

  • The most bearish analyst target is $46.00 (-20.9%).
  • Material negative event.
  • Negative session, down 4.3%.
  • Arrowhead Pharmaceuticals, Inc. moved -7.17% intraday from $71.86 to $66.71.
  • ARWR fell 3.18% to $80.22, primarily driven by profit-taking and consolidation following a strong multi-week rally, according to the web catalyst.
Bull vs bear balanceStrong Bearish Shift
BearishNeutralBullish

Weighing both sides, BestStocks' composite read of recent signals is strongly bearish, as the bull-versus-bear meter above shows. This is an educational summary of the bull and bear case, not investment advice.

Analyst price targets and ratings are FMP consensus figures as of Oct 14, 2026; other aggregators may differ. High and low targets show the range of estimates, not forecasts.

Analyst expectations
Consensus target: $101+73.1%
= 10 maintains
HC Wainwright & Co. maintained Buy · 2026-09-01
SEC filings watch
8-K2026-08-04
Material event — review for impact
high
10-Q2026-08-04
Quarterly financial results
medium
8-K2026-06-16
Material event — review for impact
high
Peer context
ARWR-4.3%

Previous notable changes for ARWR

Valuation2026-10-12-3.2%via Yahoo Finance ↗
Arrowhead Pharmaceuticals declined 3.26% to $60.70 amid profit-taking following recent pipeline catalysts and technical pressure. According to web sources, the selloff reflects investor caution after completion of Phase 3 studies for plozasiran in severe hypertriglyceridemia and entry into the FDA STAR Pilot Program, combined with prior volatility from ARO-DIMER-PA trial data disclosures and a strong multi-month run. Trading volume was light at 0.26x expected levels 220 minutes into the session, suggesting limited conviction behind the move.
Material / Earnings2026-10-09+3.3%
Arrowhead Pharmaceuticals, Inc. (ARWR) moved +3.34% after the FDA granted plozasiran entry into the STAR pilot program, accelerating the review timeline for its severe hypertriglyceridemia indication.
News2026-10-07-0.1%
FDA grants plozasiran entry into STAR pilot program, accelerating review timeline for severe hypertriglyceridemia indication.
News2026-10-06-1.3%
ARWR stock fell below its 200-day moving average of $75.86, trading at $62.35.
Upcoming catalysts & outlook
Next earnings
2026-11-24 (est.)
in 41 days
Earnings Release
2026-11-24
High impact
Thesis shift
Strong Bearish Shift
bearish signal
Risk level
High
from change events

Frequently asked questions about ARWR

Why did Arrowhead Pharmaceuticals, Inc. (ARWR) stock move?

ARWR fell 4.3% to $58.13. No single company-specific catalyst was confirmed during the move window, and it looks technical.

How much did ARWR stock fall?

ARWR lost 4.28% ($2.60) versus the prior close of $60.73, last trading at $58.13 on 1.1× average volume.

When is Arrowhead Pharmaceuticals, Inc.'s next earnings date?

ARWR's next earnings report is estimated for 2026-11-24 — about 41 days away.

What is the analyst price target for ARWR?

The consensus analyst price target for ARWR is $100.63, about 73.1% above the current $58.13. Over the past 90 days, analysts recorded 0 upgrades, 10 maintains, and 0 downgrades.

How BestStocks tracks ARWR

This page is generated automatically by BestStocks' change-detection system after its price and volume cleared ARWR-specific materiality thresholds, triggering an evidence check. It draws on 20 tracked change events for ARWR, cross-checked against the data sources listed below. Price, volume, and market-capitalization figures are the live intraday quote as of October 14, 2026 and refresh as new information is detected; for companies with multiple share classes, market-cap figures can differ by data source. Analyst price targets and ratings are FMP consensus. This is an educational summary of what changed and why — not personalized investment advice.

Data sources
FMP real-time & historical price dataSEC EDGAR filingsFMP earnings & estimatesAnalyst ratings & price targets (FMP)Earnings calendar (FMP)
Educational research tool — not personalized investment advice. Data may be delayed.