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Last update: Aug 10, 2026, 6:28 PM ET
Axsome Therapeutics, Inc.
$220.89 3.83% today
Pre-market

Why Axsome Therapeutics, Inc. (AXSM) stock moved

Updated Aug 11, 2026

Axsome Therapeutics, Inc. (AXSM) shares rose 3.8% to $220.89 as of August 11, 2026, a moderate gain from the prior close of $212.74. BestStocks flagged the session as a major change for AXSM. The move is tied to an earnings miss. Below, we break down what changed for AXSM, why it matters for investors, how the stock reacted, and the catalysts on the calendar.

What happened

Earnings Miss

AXSM rose 3.8% in its latest session, moving from $212.74 to $220.89.

Material / EarningsMedium confidence
Rel. volume
1.7×
Above Avg
Vs peers
No comparable peers
Market cap
$11.4B
NASDAQ Global Market
Analyst target
$269
+21.9% vs price
Price chart
Jul 13 – Aug 11
EVVFEEEVVFVVE$210$226$242Jul 13Jul 20Jul 28Aug 4Aug 11
E earnings
F filing
A analyst
V/N other
click a marker to highlight
Change events — click to jump to details

What it means for Axsome Therapeutics, Inc. investors

For Axsome Therapeutics, Inc. investors, the recent signals add up to a bearish shift. On the constructive side: Positive 3.8% session move; Axsome Therapeutics, Inc. (AXSM) moved +6.91% from $221.64 to $236.95 on 2026-07-21. Weighing against that: Earnings missed expectations; Axsome Therapeutics, Inc. (AXSM) moved -2.97% from $237.04 to $230.00 on 2026-07-17. Wall Street's consensus price target sits at $269.35, implying +21.9% upside from $220.89. BestStocks rates the overall signal quality medium (73/100).

AXSM price reaction

AXSM last traded at $220.89, up $8.15 (+3.83%) from the previous close of $212.74. The session traded on 1.7× average volume (above avg), so the move carried above-average conviction. Over the past month the stock has ranged between $210.13 and $241.53, and it currently sits about 34% of the way up that band.

Bullish and bearish analyst opinions on Axsome Therapeutics, Inc. (AXSM)

The consensus analyst price target on Axsome Therapeutics, Inc. (AXSM) is $269.35, 21.9% above the recent $220.89. Over the past 90 days analysts logged 0 upgrades, 5 maintains, and 0 downgrades. Here is how the bullish and bearish cases on AXSM line up.

The bullish case

  • Wall Street's consensus price target of $269.35 implies +21.9% upside from $220.89.
  • The Street's most bullish target is $380.00 (+72.0%).
  • Positive 3.8% session move.
  • Axsome Therapeutics, Inc. (AXSM) moved +6.91% from $221.64 to $236.95 on 2026-07-21.

The bearish case

  • The most bearish analyst target is $200.00 (-9.5%).
  • Earnings missed expectations.
  • Axsome Therapeutics, Inc. (AXSM) moved -2.97% from $237.04 to $230.00 on 2026-07-17.
Bull vs bear balanceBearish Shift
BearishNeutralBullish

Weighing both sides, BestStocks' composite read of recent signals is bearish, as the bull-versus-bear meter above shows. This is an educational summary of the bull and bear case, not investment advice.

Analyst price targets and ratings are FMP consensus figures as of Aug 11, 2026; other aggregators may differ. High and low targets show the range of estimates, not forecasts.

Analyst expectations
Consensus target: $269+21.9%
= 5 maintains
Mizuho maintained Outperform · 2026-07-31
SEC filings watch
8-K2026-08-10
Material event — review for impact
high
10-Q2026-08-10
Quarterly financial results
medium
8-K2026-07-15
Material event — review for impact
high
8-K2026-06-09
Material event — review for impact
high
Peer context
AXSM+3.8%

Previous notable changes for AXSM

Filings2026-08-10+3.8%
Axsome Therapeutics, Inc. (AXSM) filed a new 8-K on August 10, 2026. The filing contents were not detailed in available records.
Material / Earnings2026-08-06-1.3%
AXSM moved -1.22% from its $212.73 open to a $210.13 close on 2026-08-06.
Material / Earnings2026-08-03-3.2%
Axsome Therapeutics, Inc. (AXSM) moved -3.20% from $218.01 to $211.04 on 2026-08-03, reaching a new 30-day low on modestly elevated volume (1.5x the 5-day average). We checked news, analyst updates, SEC filings, and corporate actions — no company-specific catalyst was found.
Valuation2026-07-31-7.1%via Yahoo Finance
Axsome Therapeutics fell 6.68% to $218.97 as broader biotech sector risk-off sentiment combined with profit-taking following the stock's recent strong run near 52-week highs, per the web_catalyst synthesis. Insider sales activity from earlier in the summer, including CEO share disposals in June, continues to weigh on sentiment. Volume of 481,577 shares is tracking at 0.83x the time-adjusted expected level.

In-depth AXSM event analyses

Permanent, dated analyses of AXSM's most significant sessions.
Upcoming catalysts & outlook
Next earnings
Unknown
Thesis shift
Bearish Shift
bearish signal
Risk level
High
from change events

Frequently asked questions about AXSM

Why did Axsome Therapeutics, Inc. (AXSM) stock move?

AXSM rose 3.8% to $220.89. No single company-specific catalyst was confirmed during the move window, and it looks technical.

How much did AXSM stock rise?

AXSM gained 3.83% ($8.15) versus the prior close of $212.74, last trading at $220.89 on 1.7× average volume.

What is the analyst price target for AXSM?

The consensus analyst price target for AXSM is $269.35, about 21.9% above the current $220.89. Over the past 90 days, analysts recorded 0 upgrades, 5 maintains, and 0 downgrades.

How BestStocks tracks AXSM

This page is generated automatically by BestStocks' change-detection system after an earnings miss was detected and verified against independent data sources. It draws on 15 tracked change events for AXSM, cross-checked against the data sources listed below. Price, volume, and market-capitalization figures are the live intraday quote as of August 11, 2026 and refresh as new information is detected; for companies with multiple share classes, market-cap figures can differ by data source. Analyst price targets and ratings are FMP consensus. This is an educational summary of what changed and why — not personalized investment advice.

Data sources
FMP real-time & historical price dataFMP earnings & estimatesSEC EDGAR filingsAnalyst ratings & price targets (FMP)
Educational research tool — not personalized investment advice. Data may be delayed.