Market closed · After hours · 5:32 PM ET
Last update: Oct 9, 2026, 4:55 PM ET
Mirum Pharmaceuticals, Inc.
$86.01▲ 5.73% today
After Hours

Why Mirum Pharmaceuticals, Inc. (MIRM) stock moved

Updated Oct 9, 2026

Mirum Pharmaceuticals, Inc. (MIRM) shares climbed 5.7% to $86.01 as of October 9, 2026, a significant gain from the prior close of $81.35. BestStocks flagged the session as a major change for MIRM. Below, we break down what changed for MIRM, why it matters for investors, how the stock reacted, and the catalysts on the calendar.

What happened

MIRM climbed 5.7% to $86.01

RBC Capital raised its price target on MIRM from $135 to $155 on October 8, maintaining an Outperform rating, citing growing confidence in Mirum's expanded pipeline. The stock rose 6.15% to $86.35 on normal volume (1.01x average). The catalyst aligns with two near-term milestones: the October 2026 commercial launch of Atebrioz for fibrodysplasia ossificans progressiva (FOP), with revenues expected in early 2027, and late-September positive Phase 3 data for brelovitug in chronic hepatitis delta virus (HDV). Atebrioz launch progress and early revenue data in Q4 2026–Q1 2027; Mirum earnings on November 3, 2026 (consensus: –$0.53 EPS); any additional regulatory or clinical updates on brelovitug for HDV.

This summary describes the catalyst and move as first detected on Oct 9, 2026, 11:51 AM EDT; the stock has continued trading since, so the current price and percentage move (shown above) may be larger or smaller than the figures here.
ValuationMedium confidence
Rel. volume
1.5×
Normal
Vs peers
—
No comparable peers
Market cap
$5.2B
NASDAQ Global Market
Analyst target
$149
+73.4% vs price
Price chart
Oct 9
Not enough price data.
E earnings
F filing
A analyst
V/N other
click a marker to highlight
Change events — click to jump to details

What it means for Mirum Pharmaceuticals, Inc. investors

For Mirum Pharmaceuticals, Inc. investors, the recent signals are mixed, leaving the near-term picture neutral / mixed. On the constructive side: Material positive event; Strong 5.7% price move. Weighing against that: Mirum Pharmaceuticals shares fell 5.85% to $93.04 as investors weigh regulatory uncertainties ahead of a September 26 FDA decision on zilurgisertib for FOP and recent FDA requests for additional Phase 3 clarity on volixibat, according to the web_catalyst synthesis; New SEC filing — review for material disclosures. Wall Street's consensus price target sits at $149.10, implying +73.4% upside from $86.01. BestStocks rates the overall signal quality medium (62/100). With earnings roughly 25 days out, the next report is the most likely near-term test of the move.

MIRM price reaction

MIRM last traded at $86.01, up $4.66 (+5.73%) from the previous close of $81.35. The session traded on 1.5× average volume (normal), so participation was unremarkable.

Bullish and bearish analyst opinions on Mirum Pharmaceuticals, Inc. (MIRM)

Latest catalyststrengthens the bull case
The latest catalyst — a materially positive development — it strengthens the bull case and confirms the prevailing bullish analyst lean.

The consensus analyst price target on Mirum Pharmaceuticals, Inc. (MIRM) is $149.10, 73.4% above the recent $86.01. Over the past 90 days analysts logged 0 upgrades, 9 maintains, and 0 downgrades. Here is how the bullish and bearish cases on MIRM line up.

The bullish case

  • Wall Street's consensus price target of $149.10 implies +73.4% upside from $86.01.
  • The Street's most bullish target is $195.00 (+126.7%).
  • Material positive event.
  • Strong 5.7% price move.
  • Mirum Pharmaceuticals, Inc. (MIRM) moved +5.49% from $95.41 to $100.65 on 2026-08-07.

The bearish case

  • Mirum Pharmaceuticals shares fell 5.85% to $93.04 as investors weigh regulatory uncertainties ahead of a September 26 FDA decision on zilurgisertib for FOP and recent FDA requests for additional Phase 3 clarity on volixibat, according to the web_catalyst synthesis.
Bull vs bear balanceNeutral / Mixed
BearishNeutralBullish

Weighing both sides, BestStocks' composite read of recent signals is roughly balanced, as the bull-versus-bear meter above shows. This is an educational summary of the bull and bear case, not investment advice.

Analyst price targets and ratings are FMP consensus figures as of Oct 9, 2026; other aggregators may differ. High and low targets show the range of estimates, not forecasts.

Analyst expectations
Consensus target: $149+73.4%
= 9 maintains
RBC Capital maintained Outperform · 2026-10-08
SEC filings watch
8-K2026-09-28
Material event — review for impact
high
8-K2026-09-08
Material event — review for impact
high
10-Q2026-08-05
Quarterly financial results
medium
8-K2026-08-05
Material event — review for impact
high
Peer context
MIRM+5.7%

Previous notable changes for MIRM

Material / Earnings2026-10-06
Mirum Pharmaceuticals, Inc. (MIRM) moved -3.28% from $81.94 to $79.25 on 2026-10-06. We checked news, earnings announcements, analyst updates, SEC filings, and corporate actions — no company-specific catalyst was found. The move coincided with a new 30-day low and volume 1.3x the 5-day average.
Material / Earnings2026-10-05
Mirum Pharmaceuticals, Inc. (MIRM) moved -2.24% from $83.30 to $81.43 on 2026-10-05, reaching a new 30-day low. We checked news, earnings announcements, analyst updates, SEC filings, and corporate actions — no company-specific catalyst was found. Volume remained near its 5-day average.
News2026-10-02
Mirum's brelovitug met Phase III primary endpoint in AZURE-1 hepatitis delta study at 24 weeks.
Material / Earnings2026-09-30
Mirum Pharmaceuticals, Inc. (MIRM) moved -3.79% from $88.85 to $85.48 on 2026-09-30. We checked news, earnings announcements, analyst updates, SEC filings, and corporate actions — no company-specific catalyst was found. The decline brought MIRM to a new 30-day low, though volume remained near its 5-day average.

In-depth MIRM event analyses

Permanent, dated analyses of MIRM's most significant sessions.
Upcoming catalysts & outlook
Next earnings
2026-11-03 (est.)
in 25 days
10-Q Filing (est.)
2026-11-04
Medium impact
Thesis shift
Neutral / Mixed
bullish signal
Risk level
Medium
from change events

Frequently asked questions about MIRM

Why did Mirum Pharmaceuticals, Inc. (MIRM) stock move?

MIRM climbed 5.7% to $86.01. The move coincided with the context summarized above, though no single company-specific catalyst was independently confirmed.

How much did MIRM stock rise?

MIRM gained 5.73% ($4.66) versus the prior close of $81.35, last trading at $86.01 on 1.5× average volume.

When is Mirum Pharmaceuticals, Inc.'s next earnings date?

MIRM's next earnings report is estimated for 2026-11-03 — about 25 days away.

What is the analyst price target for MIRM?

The consensus analyst price target for MIRM is $149.10, about 73.4% above the current $86.01. Over the past 90 days, analysts recorded 0 upgrades, 9 maintains, and 0 downgrades.

How BestStocks tracks MIRM

This page is generated automatically by BestStocks' change-detection system after its price and volume cleared MIRM-specific materiality thresholds, triggering an evidence check. It draws on 20 tracked change events for MIRM, cross-checked against the data sources listed below. Price, volume, and market-capitalization figures are the live intraday quote as of October 9, 2026 and refresh as new information is detected; for companies with multiple share classes, market-cap figures can differ by data source. Analyst price targets and ratings are FMP consensus. This is an educational summary of what changed and why — not personalized investment advice.

Data sources
FMP real-time & historical price dataSEC EDGAR filingsFMP earnings & estimatesAnalyst ratings & price targets (FMP)Earnings calendar (FMP)
Educational research tool — not personalized investment advice. Data may be delayed.