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Twist Bioscience Corporation
$141.38 7.66% today
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Why Twist Bioscience Corporation (TWST) stock moved

Updated Aug 31, 2026

Twist Bioscience Corporation (TWST) shares tumbled 7.7% to $141.38 as of August 31, 2026, a significant decline from the prior close of $153.10. BestStocks flagged the session as a major change for TWST. Below, we break down what changed for TWST, why it matters for investors, how the stock reacted, and the catalysts on the calendar.

What happened

TWST fell 7.7% to $141.38

TWST tumbled 7.7% in its latest session, moving from $153.10 to $141.38.

ValuationLow confidence
Rel. volume
0.8×
Below Avg
Vs peers
No comparable peers
Market cap
$8.8B
NASDAQ Global Select
Analyst target
$105
-26.0% vs price
Price chart
Aug 31
Not enough price data.
E earnings
F filing
A analyst
V/N other
click a marker to highlight
Change events — click to jump to details

What it means for Twist Bioscience Corporation investors

For Twist Bioscience Corporation investors, the recent signals add up to a bearish shift. On the constructive side: Twist Bioscience Corporation (TWST) moved +10.34% from $113.18 to $124.88 on 2026-08-10; Twist Bioscience Corporation (TWST) moved +10.06% from $104.50 to $115.01 on 2026-08-05. Weighing against that: Material negative event; Sharp 7.7% decline — elevated risk. Wall Street's consensus price target sits at $104.67, implying -26.0% downside from $141.38. Over the past 90 days analysts logged 0 upgrades and 1 downgrade. BestStocks rates the overall signal quality low (57/100). With earnings roughly 74 days out, the next report is the most likely near-term test of the move.

TWST price reaction

TWST last traded at $141.38, down $11.72 (-7.66%) from the previous close of $153.10. The session traded on 0.8× average volume (below avg), so participation was unremarkable.

Bullish and bearish analyst opinions on Twist Bioscience Corporation (TWST)

The consensus analyst price target on Twist Bioscience Corporation (TWST) is $104.67, 26.0% below the recent $141.38. Over the past 90 days analysts logged 0 upgrades, 7 maintains, and 1 downgrade. Here is how the bullish and bearish cases on TWST line up.

The bullish case

  • Twist Bioscience Corporation (TWST) moved +10.34% from $113.18 to $124.88 on 2026-08-10.

The bearish case

  • The consensus analyst price target of $104.67 sits 26.0% below the recent $141.38, so the average target sees limited room to run.
  • The most bearish analyst target is $89.00 (-37.0%).
  • 1 analyst downgrade in the past 90 days, most recently Evercore ISI Group to In Line (2026-07-06).
  • Material negative event.
  • Sharp 7.7% decline — elevated risk.
Bull vs bear balanceBearish Shift
BearishNeutralBullish

Weighing both sides, BestStocks' composite read of recent signals is bearish, as the bull-versus-bear meter above shows. This is an educational summary of the bull and bear case, not investment advice.

Analyst price targets and ratings are FMP consensus figures as of Aug 31, 2026; other aggregators may differ. High and low targets show the range of estimates, not forecasts.

Analyst expectations
Consensus target: $105-26.0%
= 7 maintains1 downgrades
Piper Sandler maintained Overweight · 2026-08-05
SEC filings watch
8-K2026-08-05
Material event — review for impact
high
10-Q2026-08-03
Quarterly financial results
medium
8-K2026-08-03
Material event — review for impact
high
10-Q2026-05-04
Quarterly financial results
medium
Peer context
TWST-7.7%

Previous notable changes for TWST

Valuation2026-08-27via Yahoo Finance
Twist Bioscience rose 2.28% to $153.48, continuing a broader rally fueled by strong fiscal Q3 earnings (record $118.4M revenue, +23% YoY) and raised full-year 2026 guidance to $456–$457M, according to the web catalyst. Investor enthusiasm was further boosted by the Anthropic partnership announcement around AI-driven protein design and a successful $300M capital raise in August 2026. Volume remains below average at 0.62x expected for this time of session.
Material / Earnings2026-08-25
Twist Bioscience Corporation (TWST) moved +3.90% from $145.73 to $151.42 on 2026-08-25. We checked news, earnings announcements, analyst updates, SEC filings, and corporate actions — no company-specific catalyst was found. The move marks a new 30-day high for the stock.
Material / Earnings2026-08-24
Twist Bioscience Corporation (TWST) moved -2.89% from $145.00 to $140.80 on 2026-08-24. We checked news, earnings announcements, analyst updates, SEC filings, and corporate actions — no company-specific catalyst was found.
Material / Earnings2026-08-21
Twist Bioscience Corporation (TWST) moved +5.12% from $138.50 to $145.59 on 2026-08-21 following strong fiscal Q3 2026 earnings and positive catalysts. Q3 revenue reached $118.4 million, up 23% year-over-year, prompting management to raise full-year fiscal 2026 guidance to $456–$457 million. Additionally, Anthropic selected Twist as an independent evaluator for AI-designed proteins using Claude models, and the company upsized a capital raise to $300 million to fund R&D and manufacturing expansion.
Upcoming catalysts & outlook
Next earnings
2026-11-13 (est.)
in 74 days
Earnings Release
2026-11-13
High impact
Thesis shift
Bearish Shift
bearish signal
Risk level
High
from change events

Frequently asked questions about TWST

Why did Twist Bioscience Corporation (TWST) stock move?

TWST tumbled 7.7% to $141.38. No single company-specific catalyst was confirmed during the move window, and it looks technical.

How much did TWST stock fall?

TWST lost 7.66% ($11.72) versus the prior close of $153.10, last trading at $141.38 on 0.8× average volume.

When is Twist Bioscience Corporation's next earnings date?

TWST's next earnings report is estimated for 2026-11-13 — about 74 days away.

What is the analyst price target for TWST?

The consensus analyst price target for TWST is $104.67, about 26.0% below the current $141.38. Over the past 90 days, analysts recorded 0 upgrades, 7 maintains, and 1 downgrade.

How BestStocks tracks TWST

This page is generated automatically by BestStocks' change-detection system after its price and volume cleared TWST-specific materiality thresholds, triggering an evidence check. It draws on 20 tracked change events for TWST, cross-checked against the data sources listed below. Price, volume, and market-capitalization figures are the live intraday quote as of August 31, 2026 and refresh as new information is detected; for companies with multiple share classes, market-cap figures can differ by data source. Analyst price targets and ratings are FMP consensus. This is an educational summary of what changed and why — not personalized investment advice.

Data sources
FMP real-time & historical price dataSEC EDGAR filingsFMP earnings & estimatesAnalyst ratings & price targets (FMP)Earnings calendar (FMP)
Educational research tool — not personalized investment advice. Data may be delayed.