TWST shares tumbled 11.5% to $153.58 as of October 30, 2026, a sharp decline from the prior close of $173.45. BestStocks flagged the session as a major change for TWST. Below, we break down what changed for TWST, why it matters for investors, how the stock reacted, and the catalysts on the calendar.
What happened
TWST fell 11.5% to $153.57
TWST tumbled 11.5% in its latest session, moving from $173.45 to $153.58.
ValuationMedium confidence
Rel. volume
1.3×
Normal
Vs peers
—
No comparable peers
Market cap
$10.1B
NASDAQ Global Select
Analyst target
$154
+0.1% vs price
Price chart
Sep 29 – Oct 30
E earnings
F filing
A analyst
V/N other
click a marker to highlight
Change events — click to jump to details
What it means for TWST investors
For TWST investors, the recent signals are mixed, leaving the near-term picture neutral / mixed. On the constructive side: Positive price momentum; Twist Bioscience Corporation (TWST) moved +10.34% from $113.18 to $124.88 on 2026-08-10. Weighing against that: Material negative event; Sharp 11.5% decline — elevated risk. Wall Street's consensus price target sits at $153.70, implying +0.1% upside from $153.58. BestStocks rates the overall signal quality medium (61/100). With earnings roughly 13 days out, the next report is the most likely near-term test of the move.
TWST price reaction
TWST last traded at $153.58, down $19.88 (-11.46%) from the previous close of $173.45. The session traded on 1.3× average volume (normal), so participation was unremarkable. Over the past month the stock has ranged between $132.75 and $205.00, and it currently sits about 29% of the way up that band.
Bullish and bearish analyst opinions on TWST
The consensus analyst price target on TWST is $153.70, 0.1% above the recent $153.58. Over the past 90 days analysts logged 0 upgrades, 9 maintains, and 0 downgrades. Here is how the bullish and bearish cases on TWST line up.
▲ The bullish case
+Wall Street's consensus price target of $153.70 implies +0.1% upside from $153.58.
+The Street's most bullish target is $215.00 (+40.0%).
+Positive price momentum.
+Twist Bioscience Corporation (TWST) moved +10.34% from $113.18 to $124.88 on 2026-08-10.
▼ The bearish case
−The most bearish analyst target is $89.00 (-42.0%).
−Material negative event.
−Sharp 11.5% decline — elevated risk.
Bull vs bear balanceNeutral / Mixed
BearishNeutralBullish
Weighing both sides, BestStocks' composite read of recent signals is roughly balanced, as the bull-versus-bear meter above shows. This is an educational summary of the bull and bear case, not investment advice.
Analyst price targets and ratings are FMP consensus figures as of Oct 30, 2026; other aggregators may differ. High and low targets show the range of estimates, not forecasts.
Twist Bioscience rallied 10.81% to $160.95, driven by a TD Cowen analyst price-target upgrade to $190 and strong momentum in pharma/synthetic biology demand ahead of the company's November 12 earnings report (per web catalyst). Volume stood at 1.0M shares, 49% of time-adjusted average—below normal for this point in the session.
Material / Earnings2026-10-23+3.3%
Twist Bioscience Corporation (TWST) moved +5.18% from $132.95 to $139.84 on October 23, 2026. We checked news, earnings, analyst updates, filings, and corporate actions — no company-specific catalyst was found. The move appears to reflect positive momentum in the synthetic biology and biotech sectors, with volume near its 5-day average.
Material / Earnings2026-10-22-9.2%
Twist Bioscience Corporation (TWST) moved -6.02% from $144.00 to $135.34 on 2026-10-22. No company-specific catalyst was found. The decline was driven by a broader pullback in high-beta synthetic biology and biotech names, combined with technical profit-taking following the stock's multi-month run-up toward its 52-week high of $219.71.
Material / Earnings2026-10-21+4.5%
Twist Bioscience Corporation (TWST) moved +7.87% from $138.25 to $149.13 on 2026-10-21. We checked news, earnings announcements, analyst updates, SEC filings, and corporate actions — no company-specific catalyst was found. Volume was near its 5-day average, suggesting the move was not driven by unusual trading activity.
Twist Bioscience Corporation moved +6.53% intraday from $132.75 to $141.43. Twist Bioscience Corp (NASDAQ: TWST ) is up over 6% today, trading around $141.40. - Positive Momentum & Analyst Support: The stock is rebounding from recent volatility, supported by favorable analyst sentiment (such as TD Cowen raising its price target to $190 in mid-October) and ongoing interest in the company's picks-and-shovels role in AI-enabled drug discovery and synthetic DNA synthesis. - Recovery from Recent Pullbacks: TWST experienced choppy trading and profit-taking earlier in the month following a high near the $219 range, and today's session is seeing renewed buyer interest after a recent series of regulatory Form 144 filings. - Fundamental Growth: The upward movement aligns with the company's recent strong fiscal third-quarter report, which featured 23% year-over-year revenue growth and expanding gross margins driven by its semiconductor-based DNA platform. If you'd like, I can: - Summarize Twist Bioscience's upcoming earnings date (November 13, 2026) - Break down their latest Q3 financial metrics - Look at recent insider trading or institutional activity Which of those would you like to explore?
Material / Earnings2026-10-16-8.1%
TWST moved -7.74% from its $143.88 open to a $132.75 close on 2026-10-16.
Twist Bioscience shares fell 6.13% to $149.98 following profit-taking near 52-week highs compounded by sustained institutional selling and insider stock sales, per the web catalyst. ARK Invest extended a multi-week divestment across its funds (ARKK, ARKG), while executives including CEO Emily Leproust and CAO Robert Werner recently sold blocks of stock. Valuation concerns have also weighed on sentiment, with the stock cited as roughly 42.9% overvalued relative to fair value estimates (Investing.com). Volume of 894,410 shares at 130 minutes into the session tracked 0.85x the historical average—normal for this time of day.
Twist Bioscience rose 6.05% to $161.25 amid normal intraday volume (1.50x historical average). No specific catalyst was identified in today's news flow—recent headlines show routine executive share sales (SVP, president, and other insiders sold between $27k–$111k each) rather than material company developments. The move appears driven by broad market or sector momentum rather than company-specific news.
In-depth TWST event analyses
Permanent, dated analyses of TWST's most significant sessions.
TWST tumbled 11.5% to $153.58. No single company-specific catalyst was confirmed during the move window, and it looks technical.
How much did TWST stock fall?
TWST lost 11.46% ($19.88) versus the prior close of $173.45, last trading at $153.58 on 1.3× average volume.
When is TWST's next earnings date?
TWST's next earnings report is estimated for 2026-11-12 — about 13 days away.
What is the analyst price target for TWST?
The consensus analyst price target for TWST is $153.70, about 0.1% above the current $153.58. Over the past 90 days, analysts recorded 0 upgrades, 9 maintains, and 0 downgrades.
How BestStocks tracks TWST
This page is generated automatically by BestStocks' change-detection system after its price and volume cleared TWST-specific materiality thresholds, triggering an evidence check. It draws on 20 tracked change events for TWST, cross-checked against the data sources listed below. Price, volume, and market-capitalization figures are the live intraday quote as of October 30, 2026 and refresh as new information is detected; for companies with multiple share classes, market-cap figures can differ by data source. Analyst price targets and ratings are FMP consensus. This is an educational summary of what changed and why — not personalized investment advice.
