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Krystal Biotech, Inc.
$350.88 5.10% today
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Why Krystal Biotech, Inc. (KRYS) stock moved

Updated Sep 23, 2026

Krystal Biotech, Inc. (KRYS) shares climbed 5.1% to $350.88 as of September 23, 2026, a significant gain from the prior close of $333.85. BestStocks flagged the session as a major change for KRYS. The move is tied to price move up. Below, we break down what changed for KRYS, why it matters for investors, how the stock reacted, and the catalysts on the calendar.

What happened

KRYS climbed 5.1% to $350.88

KRYS climbed 5.1% in its latest session, moving from $333.85 to $350.88.

Material / EarningsLow confidence
Rel. volume
0.7×
Below Avg
Vs peers
No comparable peers
Market cap
$10.3B
NASDAQ Global Market
Analyst target
$384
+9.4% vs price
Price chart
Aug 24 – Sep 23
EEEEE$333$353$372Aug 24Aug 31Sep 9Sep 16Sep 23
E earnings
F filing
A analyst
V/N other
click a marker to highlight
Change events — click to jump to details

What it means for Krystal Biotech, Inc. investors

For Krystal Biotech, Inc. investors, the recent signals are mixed, leaving the near-term picture neutral / mixed. On the constructive side: Material positive event; Strong 5.1% price move on light volume. Weighing against that: Krystal Biotech shares fell 6.42% to $343.30, with volume running at 0.56x the historical average for this time of day; Krystal Biotech, Inc. (KRYS) moved -6.61% from $363.44 to $339.43 on 2026-07-14. Wall Street's consensus price target sits at $383.75, implying +9.4% upside from $350.88. BestStocks rates the overall signal quality low (56/100). With earnings roughly 40 days out, the next report is the most likely near-term test of the move.

KRYS price reaction

KRYS last traded at $350.88, up $17.03 (+5.10%) from the previous close of $333.85. The session traded on 0.7× average volume (below avg), so participation was unremarkable. Over the past month the stock has ranged between $333.85 and $371.47, and it currently sits about 45% of the way up that band.

Bullish and bearish analyst opinions on Krystal Biotech, Inc. (KRYS)

The consensus analyst price target on Krystal Biotech, Inc. (KRYS) is $383.75, 9.4% above the recent $350.88. Over the past 90 days analysts logged 0 upgrades, 3 maintains, and 0 downgrades. Here is how the bullish and bearish cases on KRYS line up.

The bullish case

  • Wall Street's consensus price target of $383.75 implies +9.4% upside from $350.88.
  • The Street's most bullish target is $474.00 (+35.1%).
  • Material positive event.
  • Strong 5.1% price move on light volume.
  • Krystal Biotech, Inc. (KRYS) moved +3.19% from $314.73 to $324.77 on 2026-08-04.

The bearish case

  • The most bearish analyst target is $300.00 (-14.5%).
  • Krystal Biotech shares fell 6.42% to $343.30, with volume running at 0.56x the historical average for this time of day.
  • Krystal Biotech, Inc. (KRYS) moved -6.61% from $363.44 to $339.43 on 2026-07-14.
Bull vs bear balanceNeutral / Mixed
BearishNeutralBullish

Weighing both sides, BestStocks' composite read of recent signals is roughly balanced, as the bull-versus-bear meter above shows. This is an educational summary of the bull and bear case, not investment advice.

Analyst price targets and ratings are FMP consensus figures as of Sep 23, 2026; other aggregators may differ. High and low targets show the range of estimates, not forecasts.

Analyst expectations
Consensus target: $384+9.4%
= 3 maintains
B of A Securities maintained Buy · 2026-09-21
SEC filings watch
8-K2026-08-03
Material event — review for impact
high
10-Q2026-08-03
Quarterly financial results
medium
8-K2026-07-21
Material event — review for impact
high
Peer context
KRYS+5.1%

Previous notable changes for KRYS

Material / Earnings2026-09-21-0.8%
Krystal Biotech, Inc. (KRYS) moved -2.01% from $340.69 to $333.85 on 2026-09-21. We checked news, earnings announcements, analyst updates, SEC filings, and corporate actions — no company-specific catalyst was found. The move appears to be technical, with KRYS reaching a new 30-day low on volume near its 5-day average.
Material / Earnings2026-09-14-2.0%
Krystal Biotech, Inc. (KRYS) moved -3.59% from $352.70 to $340.03 on 2026-09-14. We checked news, earnings announcements, analyst updates, SEC filings, and corporate actions — no company-specific catalyst was found. Volume remained near its 5-day average.
Material / Earnings2026-09-04-3.6%
Krystal Biotech, Inc. (KRYS) moved -3.70% from $371.99 to $358.24 on 2026-09-04. We checked news, earnings, analyst updates, SEC filings, and corporate actions — no company-specific catalyst was found. Volume was modestly elevated at 1.5x the 5-day average.
Material / Earnings2026-08-25+4.2%
Krystal Biotech, Inc. (KRYS) moved +3.60% from $343.81 to $356.19 on 2026-08-25. We checked news, earnings announcements, analyst updates, SEC filings, and corporate actions — no company-specific catalyst was found.
Upcoming catalysts & outlook
Next earnings
2026-11-02 (est.)
in 40 days
Thesis shift
Neutral / Mixed
bearish signal
Risk level
High
from change events

Frequently asked questions about KRYS

Why did Krystal Biotech, Inc. (KRYS) stock move?

KRYS climbed 5.1% to $350.88. No single company-specific catalyst was confirmed during the move window, and it looks technical.

How much did KRYS stock rise?

KRYS gained 5.10% ($17.03) versus the prior close of $333.85, last trading at $350.88 on 0.7× average volume.

When is Krystal Biotech, Inc.'s next earnings date?

KRYS's next earnings report is estimated for 2026-11-02 — about 40 days away.

What is the analyst price target for KRYS?

The consensus analyst price target for KRYS is $383.75, about 9.4% above the current $350.88. Over the past 90 days, analysts recorded 0 upgrades, 3 maintains, and 0 downgrades.

How BestStocks tracks KRYS

This page is generated automatically by BestStocks' change-detection system after price move up was detected and verified against independent data sources. It draws on 20 tracked change events for KRYS, cross-checked against the data sources listed below. Price, volume, and market-capitalization figures are the live intraday quote as of September 23, 2026 and refresh as new information is detected; for companies with multiple share classes, market-cap figures can differ by data source. Analyst price targets and ratings are FMP consensus. This is an educational summary of what changed and why — not personalized investment advice.

Data sources
FMP real-time & historical price dataSEC EDGAR filingsFMP earnings & estimatesAnalyst ratings & price targets (FMP)Earnings calendar (FMP)
Educational research tool — not personalized investment advice. Data may be delayed.